Figure 6

RLIPC stimulated GSK-3β and p-STAT-5 phosphorylation in both non-diabetic and diabetic rats. Representative Western blots (left) and quantification (right) of p-ERK1/2 (A), p-GSK-3β (B), p-AKT (C), p-STAT-3 (D) and p-STAT-5 (E) protein band densities (normalized to total protein, respectively) in sham, CON and RLIPC group in both non-diabetic and diabetic rats. Sham, sham surgery; CON, LAD ligation; RLIPC, remote liver ischemic preconditioning; D: diabetic rats. (n = 5–6, each group), data were presented as mean ± SEM. *p < 0.05 and ***p < 0.001 compared with Sham. #p < 0.05 and ###p < 0.001 compared with DM-sham. †††p < 0.001 compared with CON. ‡‡‡p < 0.001 compared with DM-CON (by one-way ANOVA).