Table 6 Validation group: ROC correlation analysis and comparison of DP-ACLF and other prognostic scores.
Variable | AUC (95% CI) | St | Cut-off value | Sensitivity | Specificity | Positive likelihood ratio | Negative likelihood ratio | Accuracy | *z statistic (p value) |
---|---|---|---|---|---|---|---|---|---|
CTP | 0.601 (0.511–0.685) | 0.051 | 11 | 0.939 | 0.351 | 0.031 | 0.010 | 74.6% | 5.647 (p < 0.001) |
MELD | 0.721 (0.636–0.796) | 0.059 | 26 | 0.606 | 0.856 | 0.269 | 0.054 | 76.2% | 3.637 (p < 0.001) |
MELD-Na | 0.740 (0.655–0.813) | 0.054 | 27 | 0.697 | 0.794 | 0.222 | 0.078 | 73.8% | 3.571 (p < 0.001) |
CLIF-SOFA | 0.701 (0.615–0.778) | 0.050 | 8 | 0.849 | 0.495 | 0.138 | 0.010 | 76.9% | 4.596 (p < 0.001) |
CLIF-C ACLF | 0.694 (0.607–0.771) | 0.055 | 48 | 0.485 | 0.887 | 0.138 | 0.043 | 74.6% | 4.534 (p < 0.001) |
COSSH-ACLF | 0.724 (0.639–0.799) | 0.051 | 6 | 0.788 | 0.577 | 0.320 | 0.043 | 77.7% | 4.446 (p < 0.001) |
DP-ACLF | 0.907 (0.843–0.951) | 0.027 | 9.7 | 0.909 | 0.784 | 1.75 | 0.078 | 85.4% | NA |