Table 7 Validation group: univariate Cox regression analysis of survival time and ACLF status with DP-ACLF and other prognostic scoring systems.

From: A dynamic prediction model for prognosis of acute-on-chronic liver failure based on the trend of clinical indicators

Variable

p value

Hazard ratio (95% CI)

Harrell’s C (95% CI)

Somer’s D (95% CI)

CTP

0.106

1.214 (0.959–1.540)

0.580 (0.504–0.664)

0.160 (0.008–0.328)

MELD

p < 0.001

1.148 (1.079–1.220)

0.700 (0.603–0.799)

0.400 (0.206–0.598)

MELD-Na

p < 0.001

1.072 (1.038–1.108)

0.715 (0.626–0.805)

0.430 (0.252–0.610)

CLIF-SOFA

p < 0.001

1.612 (1.270–2.047)

0.683 (0.630–0.773)

0.366 (0.260–0.546)

CLIF-C ACLF

p < 0.001

1.093 (1.042–1.147)

0.683 (0.590–0.780)

0.366 (0.180–0.560)

COSSH-ACLF

p < 0.001

2.736 (1.799–4.162)

0.714 (0.630–0.800)

0.428 (0.260–0.600)

DP-ACLF

p < 0.001

2.564 (2.008–3.274)

0.877 (0.832–0.923)

0.754 (0.664–0.846)