Table 5 Prognostic tumor characteristics in breast cancer patients according to their BMI (obese vs. non-obese).

From: Relationship of breast volume, obesity and central obesity with different prognostic factors of breast cancer

Variable

All patients

n = 347 (100%)

Non-obese

n = 224 (64.55%)

Obese

n = 123 (35.45%)

p

Clinical tumor size (mm)

22.63 ± 14.64

21.48 ± 14.32

23.65 ± 15.13

0.36

Pathological tumor size (mm)

24.23 ± 14.87

23.93 ± 16.13

24.50 ± 14.56

0.76

Tumor size (cm)

≤ 2 cm

151 (57.85%)

94 (59.49%)

57 (55.34%)

0.04*

> 2 cm

110 (42.15%)

64 (40.51%)

46 (44.66%)

 

Clinical stage

I

115 (41.22%)

75 (42.37%)

40 (39.22%)

0.66

II, III

143 (51.25%)

87 (49.16%)

56 (54.9%)

 

IV

21 (7.53%)

15 (8.47%)

6 (5.88%)

 

Pathological stage

Initial (I)

111 (36.75%)

76 (40%)

35 (31.25%)

0.08

Intermediate (II, III)

168 (55.63%)

97 (51.05%)

71 (63.39%)

 

Advanced (IV)

23 (7.62%)

17 (8.95% )

6 (5.36% )

 

Axillary involvement

Negative

172 (58.50%)

112 (61.20%)

54 (46.15%)

0.04*

Positive

122 (41.5%)

71 (38.80%)

63 (53.84%)

 

Histological type

Ductal

224 (94.12%)

138 (93.88%)

86 (94.5%)

0.69

Lobulillar

14 (5.88%)

9 (6.12%)

5 (5.49%)

 

Differentiation degree

1, 2

196 (71.01%)

131 (76.61%)

65 (61.9%)

0.01*

3

80 (28.99%)

40 (23.39%)

40 (38.1%)

 

Lymphovascular invasion (a)

Yes

14 (5.98%)

14 (9.4%)

0

0.13

No

220 (94.02%)

135 (90.6%)

85 (100%)

 

Ki-67 (a) (n = 84)

(+)

236 (86.45%)

151 (85.8%)

85 (87.63%)

0.28

(−)

37 (13.55%)

25 (14.2%)

12 (12.37%)

 

Ki-67 (%) (a)

24.45 ± 5.10

27.69 ± 3.10

21.57 ± 7.54

0.23

ER

(+)

269 (85.4% )

177 (86.76%)

92 (82.88%)

0.54

(−)

46 (14.6% )

27 (13.24%)

19 (17.12%)

 

PR

(+)

244 (78.46%)

159 (79.10%)

85 (77.27%)

0.85

(−)

67 (21.54%)

42 (20.9%)

25 (22.73%)

 

Cerb2 (a)

(+)

83 (29.12%)

57 (31.32%)

26 (25.24%)

0.44

(−)

202 (70.88%)

125 (68.68%)

77 (74.76%)

 

NPI

3.63 ± 1.89

3.53 ± 1.82

3.88 ± 1.95

0.17

NPI

< 2

49 (16.23%)

30 (16.30%)

19 (17.59%)

0.04*

2–2.4

55 (18.21%)

29 (15.76%)

16 (14.81%)

 

2.4–3.4

58 (19.21%)

46 (25%)

12 (11.11%)

 

3.4–5.4

53 (17.55%)

30 (16.30%)

23 (21.3%)

 

> 5.4

87 (28.81%)

49 (26.63%)

38 (35.18%)

 
  1. Data expressed as means ± standard deviation and absolute numbers and their frequencies.
  2. NPI Nottingham prognostic index.
  3. *p value < 0.05 (t-Student or Chi-squared).
  4. aAnalysis performed on the cases provided by the pathology department.
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