Table 6 Prognostic tumor characteristics in patients with breast cancer according to WHR (central obesity vs. no central obesity).

From: Relationship of breast volume, obesity and central obesity with different prognostic factors of breast cancer

Variable

All patients

n = 304 (100%)

WHR < 0.85

n = 121 (%)

WHR ≥ 0.85

n = 183 (60.19%)

p

Clinical tumor size (mm)

23.22 ± 13.86

24.41 ± 18.72

21.64 ± 12.01

0.06

Pathological tumor size (mm)

22.95 ± 12.13

21.76 ± 15.24

23.48 ± 15.27

0.39

Tumor size (cm)

≤ 2 cm

137 (60.62%)

54 (62.07%)

83 (59.71%)

0.11

> 2 cm

89 (39.38%)

33 (37.93%)

56 (40.29%)

 

Clinical stage

I

106 (43.80%)

44 (44.44%)

62 (43.36%)

0.24

II, III

118 (48.76%)

46 (46.46%)

72 (50.35%)

 

III

18 (7.44%)

9 (9.09%)

9 (6.29%)

 

Pathological stage

Initial (I)

103 (39.77%)

42 (42.42%)

61 (38.13%)

0.03

Intermediate (II, III)

136 (52.51%)

47 (47.47%)

89 (55.63%)

 

Advanced (IV)

20 (7.72%)

10 (10.11%)

10 (6.25%)

 

Axillary involvement

Negative

154 (60.87%)

58 (62.37%)

96 (60%)

0.00*

Positive

99 (39.13%)

35 (37.63%)

64 (40%)

 

Histological type

Ductal

263 (95.29%)

109 (95.61%)

154 (95.06%)

0.64

Lobulillar

13 (4.71%)

5 (4.39%)

8 (4.94%)

 

Differentiation degree

1, 2

172 (73.19%)

68 (77.77%)

104 (70.75%)

0.00*

3

63 (26.81%)

20 (22.73%)

43 (29.25%)

 

Lymphovascular invasion (a)

Yes

13 (6.05%)

5 (6.33%)

8 (5.8%)

0.02

No

202 (93.95%)

74 (93.67%)

128 (94.12%)

 

Ki-67 (a)

(+)

32 (14.16%)

16 (16.49%)

16 (13.97%)

0.13

(−)

201 (82.27%)

81 (83.51%)

120 (88.23%)

 

Ki-67 (%) (a)

25.45 ± 6.10

27.44 ± 12.23

24.90 ± 13.49

0.42

ER

(+)

232 (84.98%)

91 (83.49%)

141 (85.98%)

0.48

(−)

41 (15.02%)

18 (16.51%)

23 (14.02%)

 

PR

(+)

214 (79.55%)

85 (79.44%)

129 (79.63%)

0.29

(−)

55 (20.45%)

22 (20.56%)

33 (20.37%)

 

Cerb2 (a)

(+)

69 (28.28%)

22 (22.68%)

47 (31.97%)

0.23

(−)

175 (71.72%)

75 (77.32%)

100 (68.03%)

 

NPI

3.64 ± 1.83

3.21 ± 1.81

3.71 ± 1.84

0.04

NPI

< 2

43 (17.2%)

18 (19.35%)

25 (15.92%)

0.00*

2–2.4

44 (17.6%)

19 (20.43%)

25 (15.92%)

 

2.4–3.4

48 (19.2%)

22 (23.66%)

26 (16.56%)

 

3.4–5.4

47 (18.8%)

14 (15.05%)

33 (21.02%)

 

> 5.4

68 (27.2%)

20 (21.51%)

48 (30.57%)

 
  1. Data expressed as means ± standard deviation and absolute numbers and their frequencies.
  2. NPI Nottingham prognostic index.
  3. *p value < 0.05 (t-Student or Chi-squared).
  4. aAnalysis performed on the cases provided by the pathology department.
Back to article page