Figure 2
From: Partridge and embryonated partridge egg as new preclinical models for candidiasis
I (The body weight of the Alectoris chukar chicks at the start of experiment (day 30) and 5 days after infection (day 35) with comparison between control and Candida albicans infected birds. The infected birds showed significant weight loss compared to controls at the end of the experiment (error bars show standard error of mean; *p < 0.05).) II:(Expression levels of apoptotic-regulator genes following Candida albicans treatment. The expression level of Bax mRNA in the partridge extra-embryonic membranes is increased but the expression levels of Bcl-2, VEGF-A and VEGF-R2 are decreased in the LM-treated groups compared to controls. (Error bars show standard error of mean).III (The mean capillary area (MCA) analysis on the partridge’s extra-embryonic membrane. (a) A constant area (125 mm2) is extracted from captured image. (b) Extracted area has been converted to a binarized image. (c) Five defined areas (rectangular) without any branch vessels are selected and the percentage of the areas containing black pixels is quantified for the MCA. The black pixels of the image indicate the red color, or blood, in the original image. (d) MCA is significantly decreased in the fungus inoculated group compared to the control (error bars show standard error of mean; *p < 0.000, T test).
