Figure 3
From: Partridge and embryonated partridge egg as new preclinical models for candidiasis

I (Histopathological lesions encountered in Alectoris chukar inoculated with Candida albicans. (a) Congestion (arrow) is seen in kidney, H&E. (b) Mycelial and yeast forms of Candida albicans (arrows) are seen in spleen, PAS. (c) Congestion (arrows) is seen in liver, H&E. (d) Central vein dilatation (asterix) and hepatocellular necrosis (arrows) are seen in liver, H&E. (e) Congestion and granulomas (arrows) are seen in lung, H&E. (f) Degeneration and necrosis (arrow) are noticed in the exocrine portion of the pancreas, H&E). II (Histopathological lesions encountered in Alectoris chukar inoculated with Candida albicans. (a) Myocardial necrosis with mononuclear cell infiltration (arrow) are seen in myocardium, H&E. (b) Mycelial and yeast forms of Candida albicans (arrows) are seen in myocardium, PAS. (c) Granuloma (arrow) is seen in cerebrum, H&E. (d and e) Granuloma (arrow) is seen in the molecular and granular layer of cerebellum, respectively, H&E. (f) Granuloma with mycelial and yeast forms of Candida albicans are seen in cerebrum, PAS.) III:(Effects of systemic candidiasis in partridge on vascular apoptosis and blood vessel system (× 40). (A) H&E stained vessels in the control embryo: the embryo with normal blood vessel and adequate distribution of leukocytes. RBC's endothelial living cells seem normal. (B) H&E stained vessels in the infected embryo: decreasing and compassing of embryonic vasculature compared with the control. (C) IHC staining with Bax in the control embryo: scattered Bax positive blood cells and rarely positive endothelial and stromal cells. (D) IHC staining with Bax in the infected embryo: compassed vessels with more positive stained leukocytes and stromal cells, compared with the control group. (E) IHC staining with Bcl-2 in the control embryo: compassed with Bcl-2 IHC staining more cells are stained. (F) IHC staining with Bcl-2 in the infected embryo: compassed vessels with less positive stained leukocytes and stromal cells, compared with the control group).