Figure 4
From: Partridge and embryonated partridge egg as new preclinical models for candidiasis
I (Structural parameters of simulated proteins (a and b), Protein models of Bcl-2 and Bax (Gallus gallus), respectively The structures of Bcl-2 and Bax (Gallus gallus) were constructed using SWISS-MODEL (https://swissmodel.expasy.org/). (c and d) Ramachandran plots for protein model of Bcl-2 and Bax (Gallus gallus), respectively. Ramachandran plot was created using PROCHECK server,https://servicesn.mbi.ucla.edu/PROCHECK/). II (Molecular dynamics simulations (A) Simulated proteins solvated in SPC water (cyan) and sodium ions (orange). (B) Radius of gyration values for simulated proteins. By calculating the radius of gyration, it is revealed that the proteins remain stable, over the course of runs. ASP aspartic proteinase, PAO polyamine oxidase, TRY tryptophol). Molecular dynamics simulation was performed using the GROMACS 5.4.1 package http://www.gromacs.org/.
