Figure 7
adapted from the review article of Cvekl and Zhang (2017), and permission was obtained from Elsevier publisher.
Graphical summarization of transcriptional repression of neurosensory genes during lens differentiation by S100A4. Absence of S100A4, a calcium binding protein expressed discretely in lens fibers within the mouse eye induces aberrant differentiation programs of non-lineage photoreceptor, Müller glia and olfactory sensory neurons in association with changes in histone-3 lysine (H3K) trimethylation markings, indicating a repressive role for S100A4 in suppressing expression of sensory neuron genes during lens differentiation. Lens drawings were
