Figure 3
From: The role of gene to gene interaction in the breast’s genomic signature of pregnancy
Structural changes associated to FFTP, gene-by-gene analyses. Upper row: The X axis represents each of the 18,653 probes, and the horizontal line at value 1 represents, for each probe in the X axis, its normalized expression value for nulliparous. To show the existence of a specific genomic signature for parous and its different dimensions, the ordered relative mean expression level for each gene in the parous group is depicted by the green curve. The higher the changes associated to FFTP, the more distant the green curve. Statistical significance is marked in red. (A) Restructuration of mean expression levels and general tendency to upregulation after FFTP. (B) Existence of distinct channels and stimuli affecting the genes after FFTP. (C) Changes in the number and complexity of functions performed by each gene after FFTP. Bottom row: The X axis represents each of the 18,653 probes. For each pair of criteria, the simultaneous changes are depicted. (D) Simultaneous changes in CD and ME (ρ = -0.1383). (E) Simultaneous changes in SE and ME (ρ = 0.0974). (F) Simultaneous changes in SE and CD (ρ = 0.42633).
