Figure 6
From: The role of gene to gene interaction in the breast’s genomic signature of pregnancy
(a) Differential networks obtained from the direct comparison of parous and nulliparous groups depicted by ForceAtlas2 algorithm. For the figure on the left, the threshold of significance was set to α = 0.001, whereas α = 10−6 for the network on the right. Different colors were assigned according to the cluster class obtained by the modularity measure (see Methods). The node size is proportional to the node degree (see Methods). (b): Probability density function (PDF) of the parous, nulliparous and differential networks. Parous and nulliparous networks show very similar distributions of the correlation weights. The differential network, however, is more compactly distributed despite having a larger range of possible values (from -2 to 2). The three PDFs are shown superimposed at the bottom, highlighting the greater compactness of the differential network (in blue). Values at the extremes of the differential network correspond to the connections (correlations) with highly significant differences between parous and nulliparous networks.
