Table 3 Graph-theory parameters associated with the high-correlation specific networks (specific-networks: non-shared nodes). Those values of graph characteristics for which significant differences between nulliparous and parous were found have been marked with an asterisk.
From: The role of gene to gene interaction in the breast’s genomic signature of pregnancy
Feature | Graph parameter | High positive correlation networks | High negative correlation networks | ||||
---|---|---|---|---|---|---|---|
Parous | Nulliparous | p-value | Parous | Nulliparous | p-value | ||
Basic | Number of links | 146,223 | 110,239 | NA | 5147 | 16,296 | NA |
Average node degree | 44.08* | 25.38* | p < 0.05 | 6.86* | 12.09* | p < 0.05 | |
Integration | Characteristic path length | 8.27 | 6.67 | NA | 4.27 | 4.23 | NA |
Diameter | 24 | 23 | NA | 12 | 14 | NA | |
Segregation | Average clustering coefficient | 0.31* | 0.27* | p < 0.05 | 0.00 | 0.00 | p > 0.05 |
Modularity | 0.65* | 0.71* | p < 0.05 | 0.47* | 0.41* | p < 0.05 | |
Centrality | Eigenvector centrality | 0.23 | 0.41 | p < 0.05 | 0.02 | 0.04 | p < 0.05 |