Table 1 Cohort demographics.

From: Accelerated inflammatory aging in Alzheimer’s disease and its relation to amyloid, tau, and cognition

Clinical diagnosis

Aβ status

N

Age

Male (%)

CDRSB

MMSE

CU

–

312

71.6 ± 5.2

38.5

0.0 ± 0.0

29.1 ± 0.9

CU—validation

–

29

68.7 ± 5.3

45.8

0.0 ± 0.0

28.5 ± 1.3

SCD

–

125

69.5 ± 5.3

44.4

0.5 ± 0.7

28.7 ± 1.3

MCI

–

104

69.3 ± 5.6

67.8

1.3 ± 0.9

27.3 ± 2.0

+

150

72.3 ± 4.9

53.3

1.5 ± 0.9

26.8 ± 1.7

AD

+

139

75.5 ± 5.8

37.1

NA

21.2 ± 3.9

  1. All continuous values are reported as mean and standard deviation. Amyloid status was measured using the CSF Aβ42/40 ratio. The Aβ- CU group was used to fit the proteome-age regression models.
  2. CU Cognitively unimpaired, SCD subjective cognitive decline, MCI mild cognitive impairment, AD Alzheimer’s disease dementia.
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