Figure 3 | Scientific Reports

Figure 3

From: Optimizing proton minibeam radiotherapy by interlacing and heterogeneous tumor dose on the basis of calculated clonogenic cell survival

Figure 3

Mean cell survival for homogeneous tumor irradiation from two opposing directions (a–c) and four orthogonal directions (d–f). The tumor dose was set to 2 (a,d), 10 (b,e) or 35 Gy (c,f). “sp” is short for superposed and labels the irradiation by minibeams delivering a homogeneous tumor dose from each direction with half (2-dir) or quarter (4-dir) of the tumor dose delivered from each direction summing up to the prescribed tumor dose. The mean dose, which is the same for all irradiation modalities for homogeneous tumor irradiation, is added to each figure in green and corresponds to the y-axis on the right.

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