Figure 8 | Scientific Reports

Figure 8

From: Optimizing proton minibeam radiotherapy by interlacing and heterogeneous tumor dose on the basis of calculated clonogenic cell survival

Figure 8

Dose profile (blue) and cell survival profile (orange) for 2-dir planar minibeams with ctc = 15 mm at 9 cm depth (2-Gaussian approximation). The dotted lines mark the biologically effective beam size with a 10% survival threshold (deff,10%). The dashed lines mark the biologically effective beam size with a 50% survival threshold (deff,50%). A ctc of 15 mm was found to deliver an optimum mean cell survival even though the mean dose has to be increased by the factor fD = 1.50.

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