Figure 1 | Scientific Reports

Figure 1

From: A proline rich protein from the gingival seal around teeth exhibits antimicrobial properties against Porphyromonas gingivalis

Figure 1

In silico analysis of the rat SCPPPQ1 sequence. (a) Analysis of the amino acid content reveals the high hydrophobicity of the protein (40%) and a total net charge of + 1. (red = hydrophobic amino acids; black = positively charged amino acids; green = negatively charged amino acids; blue = other amino acids) (APD322, http://aps.unmc.edu/AP/). (b) SCPPPQ1 possesses a sequence rich in proline residues (highlighted in blue and bold). The hydrophobic residues believed to be on a same 3D surface are underlined. (c) iTASSER23 (https://zhanglab.ccmb.med.umich.edu/I-TASSER/) analysis predicts the position of helices on SCPPPQ1. (d) The Quark24 (https://zhanglab.ccmb.med.umich.edu/QUARK/) model further predicts that the red ⍺-helix corresponds to signal peptide (residues 2 to 15), the orange ⍺-helix to residues 28 to 32, and the blue ⍺-helix to residues 64 to 87, which is consistent with the iTASSER prediction.

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