Figure 3
pCR according to MVD, pMVD, GMP and the 32-gene angiogenesis signature score. Each bar represents number of patients by high and low biomarker for all patients, the bevacizumab-arm (Bev + Chemo), and the chemotherapy only-arm (Chemo). pCR (pathologic complete response) rates are presented by %-estimates and indicated by dark blue color. P values by Pearson’s chi-square (χ2) test or Fisher’s exact test. aFisher’s exact test. MVD microvessel density, pMVD proliferative microvessel density, A.S. angiogenesis signature score. Median as cut-off value.
