Table 3 Univariate analysis of risk factors for positive margins in frozen/permanent biopsies.
Variables | Positive margin | Clear margin | P value | ||
---|---|---|---|---|---|
N | % | N | % | ||
Histotype | |||||
Invasive ductal carcinoma | 12 | 16.4 | 61 | 83.6 | 0.07 |
Invasive lobular carcinoma | 3 | 60.0 | 2 | 40.0 | |
Mixed | 2 | 40.0 | 3 | 60.0 | |
Others | 2 | 33.3 | 4 | 66.7 | |
Multifocality | |||||
Yes | 10 | 29.4 | 24 | 70.6 | 0.144 |
No | 9 | 16.4 | 46 | 83.6 | |
Intraductal component | |||||
Present | 11 | 35.5 | 20 | 64.5 | 0.017 |
Absent | 8 | 13.8 | 50 | 86.2 | |
Tumor diameter (cm) | |||||
≤ 2 | 15 | 23.8 | 48 | 76.2 | 0.57 |
> 2 | 4 | 15.4 | 22 | 84.6 | |
Molecular subtype | |||||
HR + /HER2 − | 16 | 24.6 | 49 | 75.4 | 0.604 |
HR + /HER2 + | 2 | 14.3 | 12 | 85.7 | |
HR-/HER2 + | 0 | 0.0 | 3 | 100.0 | |
TN | 1 | 14.3 | 6 | 85.7 | |
Nearest margin (cm) | |||||
< 1 | 12 | 21.4 | 44 | 78.6 | 0.764 |
≥ 1 | 6 | 18.8 | 26 | 81.3 |