Table 3 Univariate analysis of risk factors for positive margins in frozen/permanent biopsies.

From: Breast-conserving surgery with 3D-printed surgical guide: a single-center, prospective clinical study

Variables

Positive margin

Clear margin

P value

N

%

N

%

Histotype

Invasive ductal carcinoma

12

16.4

61

83.6

0.07

Invasive lobular carcinoma

3

60.0

2

40.0

Mixed

2

40.0

3

60.0

Others

2

33.3

4

66.7

Multifocality

Yes

10

29.4

24

70.6

0.144

No

9

16.4

46

83.6

Intraductal component

Present

11

35.5

20

64.5

0.017

Absent

8

13.8

50

86.2

Tumor diameter (cm)

≤ 2

15

23.8

48

76.2

0.57

> 2

4

15.4

22

84.6

Molecular subtype

HR + /HER2 −

16

24.6

49

75.4

0.604

HR + /HER2 + 

2

14.3

12

85.7

HR-/HER2 + 

0

0.0

3

100.0

TN

1

14.3

6

85.7

Nearest margin (cm)

< 1

12

21.4

44

78.6

0.764

≥ 1

6

18.8

26

81.3

  1. HR hormone receptor, HER2 human epidermal growth factor receptor 2, TN triple negative.