Figure 4 | Scientific Reports

Figure 4

From: Infrared radiation from cage bedding moderates rat inflammatory and autoimmune responses in collagen-induced arthritis

Figure 4

Influence of exposure to IR fibres on the phagocytic capacity of innate immune CD11b + cells from CIA-affected rats. Representative flow cytometry histograms show latex particle phagocytosis at + 4° C and + 37° C by CD11b + cells (gated as shown in representative flow cytometry dot plots generated using FlowJo Software for Windows, Version 7.8. FlowJo, LLC, Ashland, Oregon, USA; https://www.flowjo.com.) from CIA rats housed in cages with IR fibre bedding (+IRF rats) and with standard wooden shaving bedding ( –IRF rats). Rats were transferred to cages with IR fibre bedding five days before immunization. Note that a significant difference between the groups was apparent only at 37° C. Scatter plot (created using GraphPad Prism version 7.00 for Windows, GraphPad Software, La Jolla, California, USA; https://www.graphpad.com) indicates the percentage of phagocyting (latex +) cells among CD11b + cells from the spleen of +IRF and –IRF rats (see Material and Methods). Results are expressed as mean ± SEM. n = 10 rats/group. *** p ≤ 0.001.

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