Figure 2
From: Approximate conditional phenotype analysis based on genome wide association summary statistics

Estimated effect sizes, − log10 (p-values) and quantile–quantile plots for GWAS with continuous outcomes measured in the Framingham Heart Study. Panels (A–C) present the estimated effect sizes, − log10 (p-values), and quantile–quantile plot (q-q plot), respectively, for GWAS results from analyzing waist circumference (WC) adjusted for body mass index (BMI); panels (D–F) present the estimated effect sizes, − log10 (p-values), and q-q plot, respectively, for BMI adjusted for ever-smoking.