Figure 2 | Scientific Reports

Figure 2

From: In-depth quantitative proteomic characterization of organotypic hippocampal slice culture reveals sex-specific differences in biochemical pathways

Figure 2

Biosynthetic pathways of glycerophospholipids in rat hippocampus. Glycerophospholipids are synthetized in the Kennedy pathway and subsequently remodeled in the Lands cycle, contributing to lipid diversity and the production of intracellular lipid mediators. The differentially expressed proteins revealed by proteomics in organotypic hippocampal slice culture are highlighted in pink (increased abundance in female) and blue (increased abundance in males). For more details, see Supplementary Dataset 1. Statistical analyses were performed by using Student's t test followed by multiple testing corrections using the Benjamini–Hochberg procedure for false discovery rate (n = 5 biological replicates, each containing 3 slices).

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