Table 4 Subgroup analysis for pooled prevalence of CD in Asian-Pacific region among at-risk and not at-risk populations.

From: Prevalence of celiac disease in low and high risk population in Asia–Pacific region: a systematic review and meta-analysis

 

Sero-prevalence in not at-risk population

Biopsy-confirmed prevalence in not at-risk population

Biopsy-confirmed prevalence in at-risk population

N. patients

N. subjects

Pooled prevalence

P-value

N. patients

N. subjects

Pooled prevalence

P-value

N. patients

N. subjects

Pooled prevalence

P-value

Population

Adult

310

56,707

1.01%

0.01

170

26,738

0.55%

0.02

80

2282

3.13%

0.08

Children

664

28,904

2.01%

193

33,118

0.66%

308

6396

5.28%

Adults and children

151

10,488

1.44%

109

10,488

1.04%

97

1454

4.71%

Sex

Male

394

45,074

0.8%

0.04

163

30,345

0.53%

0.04

244

4384

4.02%

0.43

Female

543

37,597

1.65%

182

23,592

0.74%

183

5021

4.82%

Region

Oceania

 < 0.001

20

4075

0.61%

 < 0.001

187

4434

4.22%

 < 0.001

Middle East

647

31,452

1.47%

215

38,538

0.59%

233

5226

4.07%

South Asia

467

44,869

1.25%

236

25,723

0.87%

49

723

7.10%

East Asia

11

19,778

0.06%

1

2008

0.05%

16

337

3.65%

Risk of CD

DS

 

10

306

2.90%

0.05

DM1

 

274

6145

5.06%

Chronic diarrhea

 

68

943

8.43%

ATD

 

15

691

2.94%

Dyspeptic

 

10

407

2.46%

FDR

 

49

1009

4.85%

IBD

 

58

1172

2.62%

Abdominal pain

 

1

47

2.13%

  1. DM1 Diabetes Mellitus type1, DS Down syndrome, IBD Inflammatory bowel disease, ATD autoimmune thyroiditis diseases, FDR first-degree relatives.