Table 8 Examples of the relationship between features and class prediction.
First Layer | Most influential feature | CDRSB | Clinical dementia rating sum of box score |
|---|---|---|---|
Lowest important feature | TRABSCOR PartBTimeToComplete | Neuropsychological battery’s TRABSCOR trail making test (part B—time to complete) | |
The best feature for AD class | MMSE | Mini-Mental State Examination | |
The best feature for CN and MCI classes | CDRSB | Clinical dementia rating sum of box score | |
\(\uparrow\) CDRSB, \(\downarrow\) ADNI_MEM | \(\uparrow\) risk for the AD class | Sensitivity of the AD class to this list of features | |
\(\downarrow\) CDRSB, \(\uparrow\) ADNI_MEM, \(\uparrow\) DigitalTotalScore, \(\uparrow\) MOCA | \(\uparrow\) chance for the CN class | Sensitivity of the CN class to this list of features | |
\(\downarrow\) CDRSB, \(\uparrow\) FAQ,\(\uparrow\) MOCA, \(\uparrow\) CDGLOBAL, \(\downarrow\) ADNI_MEM | \(\downarrow\) risk for the MCI class | Sensitivity of the MCI class to this list of features |
Second Layer | Most influential feature | ADNI_MEM | ADNI_MEM is composite logical memory score for the8 longitudinal changes in memory |
|---|---|---|---|
Lowest important feature | Trail4Total | Neuropsychological Battery AVTOT4 feature | |
\(\uparrow\) FAQ, \(\uparrow\) RAVLT_immediate | \(\uparrow\) chance for the sMCI class | Relationship between RAVLT_immediate and sMCI class | |
\(\uparrow\) FAQ, \(\uparrow\) RAVLT_immediate | \(\downarrow\) risk for the pMCI class | Relationship between FAQ and RAVLT_immediate and pMCI class | |
\(\uparrow\) ADAS 13, \(\uparrow\) ADNI_MEM, \(\downarrow\) FDG, \(\downarrow\) MOCA | \(\uparrow\) risk for the pMCI class | Relationship between ADAS, ADNI_MEM, FDG, and MOCA and pMCI class |
