Table 2 Comparison of OCT-based factors in control eyes and at different stages of diabetic retinopathy.
From: Factors based on optical coherence tomography correlated with vision impairment in diabetic patients
Variable | Control eyes (n = 62) | Stage of DR | |||
|---|---|---|---|---|---|
NDR (n = 92) | NPDR (n = 67) | PDR (n = 24) | P value | ||
OCT B and C-scan metrics | |||||
CRT in central subfield by ETDRS grid (μm) | 248 ± 17 | 255 ± 23 | 290 ± 73bd | 351 ± 131bd | < 0.001 |
Frequency of DRIL (%) | 0.0 | 0.0 | 16.4 | 41.7 | < 0.001 |
Length of DRIL (μm) | 0.0 | 0.0 | 123 ± 309bd | 330 ± 487bd | < 0.001 |
Frequency of HF in total retinal layer (%) | 11.3 | 26.1 | 56.7 | 75.0 | < 0.001 |
Number of HF in total retinal layer (n) | 0.2 ± 0.6 | 0.5 ± 1.4 | 2.4 ± 4.6bd | 8.0 ± 10.3bde | < 0.001 |
Frequency of HF in inner retinal layer (%) | 11.3 | 22.8 | 55.2 | 70.8 | < 0.001 |
Number of HF in inner retinal layer (n) | 0.2 ± 0.6 | 0.4 ± 0.9 | 1.8 ± 3.0bd | 4.8 ± 6.0bd | < 0.001 |
Frequency of HF in outer retinal layer (%) | 0.0 | 3.3 | 17.9 | 62.5 | < 0.005 |
Number of HF in outer retinal layer (n) | 0.0 | 0.0 ± 0.2 | 0.6 ± 1.8bd | 3.2 ± 5.0bdf | < 0.001 |
Frequency of IRF (%) | 0.0 | 0.0 | 28.4 | 41.7 | < 0.001 |
Height of IRF (μm) | 0.0 | 0.0 | 47 ± 99bd | 99 ± 157bd | < 0.001 |
Frequency of SRF (%) | 0.0 | 0.0 | 9.0 | 20.8 | < 0.001 |
Height of SRF (μm) | 0.0 | 0.0 | 6 ± 24c | 29 ± 65bd | < 0.001 |
Frequency of ELM disruption (%) | 0.0 | 0.0 | 4.5 | 8.3 | 0.07 |
Length of ELM disruption (μm) | 0.0 | 0.0 | 39 ± 206 | 97 ± 337c | < 0.05 |
Frequency of EZ disruption (%) | 0.0 | 0.0 | 10.4 | 54.2 | < 0.01 |
Length of EZ disruption (μm) | 0.0 | 0.0 | 80 ± 257ad | 575 ± 602bdf | < 0.001 |
OCTA metrics | |||||
VD of SCP in central subfield by ETDRS grid (%) | 19.3 ± 6.2 | 21.0 ± 5.9 | 18.8 ± 6.7 | 24.8 ± 8.8ae | < 0.01 |
FAZ area (mm2) | 0.31 ± 0.09 | 0.28 ± 0.10 | 0.32 ± 0.13 | 0.38 ± 0.27 | 0.06 |
FAZ circularity | 0.72 ± 0.08 | 0.71 ± 0.08 | 0.63 ± 0.11bd | 0.58 ± 0.15bd | < 0.001 |
