Figure 2

Comparison of neutralisation of H7N9 by monovalent and bivalent NB7-14. Pseudotype micro-neutralisation assay performed using influenza A/Shanghai/02/2013 (H7) HA bearing pseudovirus and mono- and bivalent nanobody NB7-14. Percentage neutralisation is plotted against molar concentration of NB7-14 in two different formats (nM). IC50 for monovalent NB7-14 (17 nM) and for bivalent NB7-14 (130 pM). Neutralisation of A/Texas/50/2012 (H3N2) was negative (data not shown).