Figure 6 | Scientific Reports

Figure 6

From: Nanobodies mapped to cross-reactive and divergent epitopes on A(H7N9) influenza hemagglutinin using yeast display

Figure 6

Correlation of epitope Gp2 specificity to natural sequence divergence. (a) Correlation of binding of NB7-03 (Gp3) and NB7-14 (Gp1a) to natural sequence divergence at K164. (b) ELISA of purified NB7-14 (red) and NB7-03 (green) binding to inactivated whole virus antigen preparations from the following: A/Guangdong/17SF003/2016 (H7N9); A/Anhui/01/2013 (H7N9) and A/Hong Kong/125/2017 (H7N9). (c) Confirmation of specificity of NB7-03 and NB7-14 to yeast cells displaying the HA1-K164E mutation.

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