Table 4 Risk factors associated with in-hospital death.
From: Key factors leading to fatal outcomes in COVID-19 patients with cardiac injury
Univariable OR (95% CI) | p value | Multvariable OR (95% CI) | p value | |
|---|---|---|---|---|
Demographics and complications of COVID-19 patients with cardiac injury | ||||
Age, years | 1.02 (1.00–1.05) | .012 | 1.12 (1.05–1.18) | < .001 |
Acute liver injury | 2.41 (1.06–5.50) | .035 | 1.44 (0.58–3.53) | .423 |
Acute kidney injury | 2.55 (1.35–4.83) | .004 | 1.79 (0.89–3.57) | .098 |
Coagulopathy | 3.31 (1.73–6.33) | < .001 | 2.54 (1.26–5.12) | .009 |
ARDS | 13.43 (6.00–30.08) | < .001 | 16.56 (6.66–41.20) | < .001 |
Laboratory findings of COVID-19 patients with cardiac injury | ||||
Leukocyte count, × 109/L | 1.10 (1.02–1.18) | .007 | – | – |
Neutrophil count, × 109/L | 1.13 (1.05–1.23) | .001 | – | – |
Lymphocyte count, × 109/L | 0.02 (0.08–0.46) | < .001 | – | – |
Platelet count, × 109/L | 0.99 (0.98–0.99) | .002 | – | – |
Prothrombin time, s | 1.41 (1.11–1.79) | .005 | – | – |
Activated partial thrombin time, s | 1.08 (1.01–1.15) | .012 | – | – |
D-dimer, mg/L | 1.02 (1.00–1.03) | .008 | – | – |
Lactate dehydrogenase, U/L | 1.00 (1.00–1.00) | .362 | 1.00 (1.00–1.00) | .01 |
Total bilirubin, μmol/L | 1.03 (1.00–1.07) | .019 | – | – |
Blood urea nitrogen, mmol/L | 1.06 (1.01–1.10) | .004 | – | – |
Hypersensitive troponin I, ng/mL | 7.95 (2.64–23.87) | < .001 | 4.54 (1.79–11.48) | .001 |
C-reactive protein, mg/L | 1.01 (1.00–1.01) | < .001 | – | – |
Procalcitonin, ng/mL | 2.90 (1.55–5.42) | .001 | – | – |
CD8 count, μL−1 | 0.99 (0.99–0.99) | .005 | – | – |
CD4 count, μL−1 | 0.99 (0.99–0.99) | < .001 | 0.99 (0.99–1.00) | .057 |
IL-6, pg/mL | 1.01 (1.00–1.02) | < .001 | 1.01 (1.00–1.02) | .017 |
