Table 4 Summary of HLA alleles associated with SJS/TEN with ocular complications.
Allele | Phenotype | Ethnic group | Reference |
|---|---|---|---|
Negative associations—Protective alleles | |||
B*0702 | British | Present Study | |
A*1101 | Brazilian | ||
Japanese | |||
A*2402 | CM SOC | Japanese | |
HLA—DQB1*0502 | Japanese | ||
B*0801 | SOC | Brazilian | |
B*5101 | SOC | Brazilian | |
B*5701 | Indian | ||
C*0303 | Korean | ||
C*0602 | Indian | ||
Positive associations—Risk alleles | |||
A*0206 | CM SOC | Japanese | |
Korean | |||
A*3303 | Indian | ||
A*6601 | SOC | Brazilian Padro and European ancestry | |
SOC | Brazilian | ||
B*1301 | CM SOC | Japanese | |
B*4403 | CM SOC | Japanese | |
SOC | Indian | ||
CM SOC | Thai | ||
SOC | Brazilian | ||
Indian | |||
Brazilian | |||
Brazilian of European ancestry | |||
B*5801 | Korean | ||
C*0304 | SOC | Korean | |
C*0701 | SOC | Indian | |
C*1403 | CM SOC | Japanese | |
C*1203 | SOC | Brazilian | |
Brazilian of European ancestry | |||
HLA-DQB1*0601 | European | ||
Haplotypes | |||
A*3303-C*1403-B*4403 | SOC | Japanese | |
B*4403-C*0701 | Thai | ||
