Figure 7
From: Decision theory for precision therapy of breast cancer
Alluvial flow diagram for patients originally diagnosed by ODDS and then checked by DST. Left margin: Hormone receptor assessed by method sODDS: positive (H+) and negative (H−). A sample was considered H+ if at least one receptor was positive. Lacking IHC estimates were imputed by ODDS and included only if imputation was safe, otherwise discarded. Hence, no patients with receptor status ‘undetermined’ appear in dataset subjected to DST. Right margin: Evaluation by DST confirms the vast majority of estimates from sODDS but leaves some 153 as undetermined (ochre colored). Only one patient is definitely considered false negative and changed to positive.
