Table 2 Enzyme kinetics studies with PfM1AAP.

From: Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP)

Substrate

pH

Km (µM)

Kcat (s−1)

Kcat/Km (M−1S−1)

Kcat/Km (7:5/5:5 ratio)

Ala

7.5

197

0.9

4394.5

15.9

5.2

1276

0.4

276.7

Leu

7.5

197

0.8

4139.4

10.2

5.2

1714

0.7

407.3

Arg

7.5

308

0.7

2335.3

5.6

5.2

980

0.4

420.3

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