Table 3 Required number of patient samples per clinical subgroup and the percentage of proteins in the SWATH-MS dataset which would meet the statistical criteria at a statistical power of 95%, 75% or 50%.

From: Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells

Number of patient samples per clinical subgroup

% of proteins in dataset* which meet statistical criteria

95% power

75% power

50% power

5

0

0

0

10

32

45

53

20

57

63

68

30

64

71

80

40

70

79

95

50

76

90

100

75

93

100

100

100

100

100

100

  1. The total dataset consisted of 5108 proteins. The calculations were based on a twofold change and a 0.1 Bonferroni adjusted P-value.
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