Figure 6 | Scientific Reports

Figure 6

From: Non-linearity of end-systolic pressure–volume relation in afterload increases is caused by an overlay of shortening deactivation and the Frank–Starling mechanism

Figure 6

Pressure volume loops of an afterload intervention with the associated end-systolic pressure volume relationships (ESPVR) obtained from the first (PLoad bilin1) and second phases (PLoad bilin2). The end-systolic values (black dots) of PLoad bilin1 are components of different ESPVRs (dotted red lines) with a slope equal to that of the ESPVR bilin2 values. Phase 1 reflects the mechanism of “shortening deactivation”, and phase 2 represents the Frank-Starling mechanism or “fast force response”.

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