Figure 4 | Scientific Reports

Figure 4

From: Transcriptional response to the host cell environment of a multidrug-resistant Mycobacterium tuberculosis clonal outbreak Beijing strain reveals its pathogenic features

Figure 4

Expression levels of genes in the cholesterol degradation pathway. (a–i) THP-1 macrophages were infected with the M. tuberculosis reference strain H37Rv (H) or the MKR superspreader (M) for 4 h. The expression levels of various genes in the cholesterol degradation pathway were quantified by qRT-PCR. 2-∆∆ct is used for normalisation and relative quantification. One-way ANOVA with Tukey's multiple comparison test was used to determine which pairs of expression levels were significantly different (*: p < 0.05; **: p < 0.01; and ***: p < 0.001).

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