Table 3 Haplotype frequencies and genotype counts in Japanese vaccines (high-responders), Japanese chronic hepatitis B patients, and healthy Japanese individuals.

From: Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines

 

DRB1*13:02-DQB1*06:04

Frequencies

Genotype counts

Heptavax-II recipients

2.8%*

17/610

Bimmugen recipients

6.8%

93/1372

HBV patients

2.3%**

37/1630

Healthy individuals

6.4%

291/4562

  1. *Significant association was identified in comparison with healthy Japanese individuals (OR = 0.34, P = 4.30 × 10−4).
  2. **Significant association was identified in comparison with healthy Japanese individuals (OR = 0.42, P = 2.05 × 10−10).