Table 2 Effects of antithrombotic drugs on the results of fecal immunochemical test in colorectal neoplasms screening.

From: Effects of antithrombotic drugs on the results of fecal immunochemical test in colorectal neoplasms screening

Measure

Outcome

Anti-thrombotic agents

p-value

Yes (n = 144)

No (n = 614)

Sensitivity

CN

38/61 (62.3%)

CI (49.0–74.4%)

122/217 (56.0%)

CI (49.3–62.9%)

0.3964

CRC

11/14 (78.6%)

CI (49.2–95.3%)

35/43 (81.4%)

CI (66.6–91.6%)

0.8161

CRC + AA

21/29 (72.4%)

CI (52.8–87.3%)

75/99 (75.8%)

CI (66.1–83.8%)

0.7146

NAA only

17/32 (53.1%)

CI (34.7–70.9%)

47/118 (39.8%)

CI (30.9–49.3%)

0.1775

Specificity

CN

50/83 (60.2%)

CI (48.9–70.8%)

223/397 (56.2%)

CI (51.1–61.1%)

0.4960

CRC

70/130 (53.9%)

CI (44.9–62.6%)

310/571 (54.3%)

CI (50.1–58.4%)

0.9268

CRC + AA

65/115 (56.5%)

CI (47.0–65.7%)

294/515 (57.1%)

CI (52.7–61.4%)

0.9118

NAA only

50/83 (60.2%)

CI (48.9–70.8%)

223/397 (56.2%)

CI (51.1–61.1%)

0.4960

PPV

CN

38/71 (53.5%)

CI (41.3–65.5%)

122/296 (41.2%)

CI (35.6–47.1%)

0.0604

CRC

11/71 (15.5%)

CI (8.0–26.0%)

35/296 (11.8%)

CI (8.4–16.1%)

0.4018

CRC + AA

21/71 (29.6%)

CI (19.3–41.6%)

75/296 (25.3%)

CI (20.5–30.7%)

0.4654

NAA only

17/50 (34.0%)

CI (21.2–48.8%)

47/221 (21.3%)

CI (16.1–27.3%)

0.0556

NPV

CN

50/73 (68.5%)

CI (56.6–78.9%)

223/318 (70.1%)

CI (64.8–75.1%)

0.7840

CRC

70/73 (95.9%)

CI (88.5–99.1%)

310/318 (97.5%)

CI (95.1–98.9%)

0.4576

CRC + AA

65/73 (89.0%)

CI (79.5–95.1%)

294/318 (92.5%)

CI (89.0–95.1%)

0.3376

NAA only

50/65 (76.9%)

CI (64.8–86.5%)

223/294 (75.9%)

CI (70.5–80.6%)

0.8545

  1. CN colorectal neoplasms, CRC colorectal cancer, AA advanced adenoma, NAA non advanced adenoma, PPV positive predictive value, NPV negative predictive value, CI confidence interval.