Table 3 Effects of antiplatelet drugs on the results of fecal immunochemical test in colorectal neoplasms screening.

From: Effects of antithrombotic drugs on the results of fecal immunochemical test in colorectal neoplasms screening

Measure

Outcome

Anti-platelet agents

p-value

Yes (n = 129)

No (n = 614)

Sensitivity

CN

31/53 (58.5%)

CI (44.1–71.9%)

122/217 (56.0%)

CI (49.3–62.9%)

0.7650

CRC

8/10 (80.0%)

CI (37.7–56.5%)

35/43 (81.4%)

CI (66.6–91.6%)

0.9191

CRC + AA

17/24 (70.8%)

CI (48.9–87.4%)

75/99 (75.8%)

CI (66.1–83.8%)

0.6182

NAA only

14/30 (46.7%)

CI (28.3–65.7%)

47/118 (39.8%)

CI (30.9–49.3%)

0.4970

Specificity

CN

47/76 (61.8%)

CI (50.0–72.8%)

223/397 (56.2%)

CI (51.1–61.1%)

0.3602

CRC

67/119 (56.3%)

CI (46.9–65.4%)

310/571 (54.3%)

CI (50.1–58.4%)

0.6884

CRC + AA

62/105 (59.0%)

CI (52.7–61.4%)

294/515 (57.1%)

CI (52.7–61.4%)

0.6563

NAA only

47/76 (61.8%)

CI (50.0–72.8%)

223/397 (56.2%)

CI (51.1–61.1%)

0.3602

PPV

CN

31/60 (51.7%)

CI (38.4–64.8%)

122/296 (41.2%)

CI (35.6–47.1%)

0.1360

CRC

8/60 (13.3%)

CI (5.9–24.6%)

35/296 (11.8%)

CI (8.4–16.1%)

0.7436

CRC + AA

17/60 (28.3%)

CI (17.5–41.4%)

75/296 (25.3%)

CI (20.5–30.7%)

0.6289

NAA only

14/43 (32.6%)

CI (19.1–48.5%)

47/221 (21.3%)

CI (16.1–27.3%)

0.1080

NPV

CN

47/69 (68.1%)

CI (55.8–78.8%)

223/318 (70.1%)

CI (64.8–75.1%)

0.7418

CRC

67/69 (97.1%)

CI (89.9–99.6%)

310/318 (97.5%)

CI (95.1–98.9%)

0.8558

CRC + AA

62/69 (89.9%)

CI (80.2–95.8%)

294/318 (92.5%)

CI (89.0–95.1%)

0.4712

NAA only

47/63 (74.6%)

CI (62.1–84.7%)

223/294 (75.9%)

CI (70.5–80.6%)

0.8343

  1. CN colorectal neoplasms, CRC colorectal cancer, AA advanced adenoma, NAA non advanced adenoma, PPV positive predictive value, NPV negative predictive value, CI confidence interval.