Table 2 Patient days, DOT–LOT per 100 patient days and DOT/LOT ratio calculated for antibiotics provided for therapeutic purposes by sex, age classes, hospital ward, lenght of hospital stay, comorbidities and participating center.
From: Use of multiple metrics to assess antibiotic use in Italian children’s hospitals
Number of patient days | DOT/100 patient days | P valueDOT | LOT/100 patient days | P valueLOT | DOT/LOT ratio | |
|---|---|---|---|---|---|---|
Sex | ||||||
Male | 4779 | 33.9 | < 0.001 | 20.7 | < 0.001 | 1.6 |
Female | 4653 | 27.8 | 17.8 | 1.6 | ||
Age classes | ||||||
0–11 months | 1496 | 30.1 | < 0.001 | 19.0 | < 0.001 | 1.6 |
12–23 months | 2063 | 40.3 | 24.8 | 1.6 | ||
2–4 years | 1996 | 26.5 | 18.4 | 1.4 | ||
5–9 years | 1282 | 33.5 | 18.5 | 1.8 | ||
≥ 10 years | 2680 | 25.1 | 15.7 | 1.6 | ||
Ward | ||||||
Medical | 5362 | 29.7 | < 0.001 | 18.6 | < 0.001 | 1.6 |
Surgical | 2450 | 20.6 | 13.4 | 1.5 | ||
Intensive Care | 1736 | 47.2 | 28.5 | 1.7 | ||
Length of hospital stay (days) | ||||||
≤ 7 | 4154 | 30.5 | 0.7 | 17.9 | < 0.001 | 1.7 |
08–30 | 1816 | 31.3 | 22.0 | 1.4 | ||
> 30 | 3578 | 30.2 | 18.8 | 1.6 | ||
Comorbidities | ||||||
Yes | 4343 | 27.3 | < 0.001 | 20.1 | < 0.001 | 1.3 |
No | 4884 | 33.6 | 17.7 | 1.9 | ||
Participating center | ||||||
1 | 5799 | 34.6 | < 0.001 | 21.3 | < 0.001 | 1.6 |
2 | 1612 | 40.6 | 24.9 | 1.6 | ||
3 | 251 | 31.1 | 20.7 | 1.5 | ||
4 | 1886 | 9.3 | 7.1 | 1.3 | ||
Total | 9548 | 30.5 | 19.1 | 1.6 | ||
