Table 3 Resting state pairwise connections in individuals with food addiction compared to individuals with no food addiction.

From: Alterations in reward network functional connectivity are associated with increased food addiction in obese individuals

Food addiction versus no food addiction

Network

Analysis unit

Network

Analysis unit

df

t

p-value

q-value

Interpretation

Brainstem 113 connections

Bst

L MRF

CEN

L_MFG (R_ContB_PFClv_3)

146

4.05

8.28E−05

0.02

Greater

Bst

L_MRF

CAN

R_OrG, (R_ContB_PFClv_2)

146

3.98

1.08E−04

0.02

Greater

Bst

L_MRF

CAN

L_OrG, (L_ContB_PFClv_1)

146

3.89

1.52E−04

0.02

Greater

Emotional regulation (ERN) network connections

ERN

L_InfFS, (R_ContA_PFCl_2)

SMN

R_PosCG, (R_SomMotA_16)

146

− 4.00

1.00E−04

0.04

Lower

Sensorimotor (SMN) network connections

SMN

R_PosCG, (R_SomMotA_16)

DMN

R_MTG, (R_TempPar_6)

146

− 4.11

6.57E−05

0.03

Lower

  1. Summarizes significant disease-related differences in functional connectivity (individuals with food addiction vs. individuals with no food addiction). All connections are significant q < 0.05.
  2. Bst, Brainstem; CAN, Central Autonomic Network; CEN, Central Executive Network; DMN, Default Mode Network; ERN, Emotional Regulation Network; InfFS, Inferior frontal sulcus; MFG, Middle frontal gyrus; MRF, Mesencephalic reticular formation; MTG, Middle Temporal Gyrus; OrG, Orbital gyri; PosCG, Postcentral Gyrus; SMN, Sensorimotor Network.
  3. df: degrees of freedom; p value significant < .05, q value (corrected for multiple comparisons) < .05.
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