Table 3 Characteristics of the treatments.

From: Correlation between toxicity and dosimetric parameters for adjuvant intensity modulated radiation therapy of breast cancer: a prospective study

Treatments

Surgery (n = 288)

Type of surgery

 Partial mastectomy

170 (59.0%)

 Bilateral partial mastectomy

7 (2.4%)

 Lumpectomy

3 (1.0%)

 Total mastectomy

99 (34.4%)

 Bilateral total mastectomy

3 (1.0%)

 Total mastectomy on one side and partial mastectomy on the other

6 (2.1%)

Axillary node dissection

205 (71.2%)

Sentinel lymph node

176 (61.1%)

Chemotherapy (n = 288)

Any type

209 (72.6%)

Adjuvant

159 (55.2%)

Neo-adjuvant

61 (21.2%)

Hormone therapy (n = 283)

Any type

227 (80.2%)

Tamoxifen-based

90 (31.8%)

Radiotherapy

Breast or chest wall PTV (n = 288)

 D50% (mean ± SD) (Gy)

49.8 ± 0.8

 D95% (mean ± SD) (Gy)

47.0 ± 2.9

 D2% (mean ± SD) (Gy)

56.5 ± 4.1

Concomitant boost PTV (n = 167)

 D50% (mean ± SD) (Gy)

59.4 ± 1.0

 D95% (mean ± SD) (Gy)

57.2 ± 1.2

 D2% (mean ± SD) (Gy)

61.2 ± 1.2

Internal mammary chain PTV (n = 258)

 D50% (mean ± SD) (Gy)

49.5 ± 1.8

 D95% (mean ± SD) (Gy)

46.9 ± 3.6

 D2% (mean ± SD) (Gy)

52.1 ± (1.6

Subclavicular* PTV (n = 253)

 D50% (mean ± SD) (Gy)

49.6 ± 1.3

 D95% (mean ± SD) (Gy)

47.1 ± 2.1

 D2% (mean ± SD) (Gy)

51.9 ± 1.1

Supraclavicular** PTV (n = 258)

 D50% (mean ± SD) (Gy)

49.9 ± 1.4

 D95% (mean ± SD) (Gy)

48.2 ± 2.0

 D2% (mean ± SD) (Gy)

52.0 ± 1.1

  1. Data are quoted as the n (%) or the mean ± standard deviation (SD).
  2. PTV planning target volume, Dx% dose received by at least x% of the volume.
  3. *2 and 3 areas, according to ESTRO guidelines.
  4. **Area 4, according to ESTRO guidelines.