Table 2 Local maxima in clusters found through Spearman correlation of anxiety scores and amygdala functional connectivity.

Area	MNI coordinates at local maximum	Spearman’s rho at local maximum	p value
Analysis 1^a
Cluster 1
Left inferior parietal lobule	− 49, − 23, 36^c	− 0.56	1.0 × 10^–5
Left insula	− 28, − 23, 12	− 0.38	3.7 × 10^–3
Left paracentral lobule	− 4, − 32, 63	− 0.40	2.9 × 10^–3
Left superior frontal gyrus	− 22, − 8, 45	− 0.40	2.6 × 10^–3
Left SMA	− 13, − 5, 45	− 0.35	1.0 × 10^–2
Right middle cingulate	14, − 11, 48	− 0.36	7.2 × 10^–3
Analysis 2^b
Cluster 1
Left postcentral gyrus	− 46, − 17, 39^c	− 0.59	1.0 × 10^–5
Left superior parietal lobule	− 37, − 41, 54	− 0.53	6.0 × 10^–5
Left precentral gyrus	− 28, − 17, 54	− 0.48	4.6 × 10^–4
Cluster 2
Right postcentral gyrus	50, − 11, 30^c	− 0.53	9.0 × 10^–5
Right inferior parietal lobule	50, − 32, 54	− 0.50	2.3 × 10^–4
Right superior frontal gyrus	20, − 5, 48	− 0.49	2.8 × 10^–4

Cluster 1: 2857 voxels (rho = − 0.50; p = 1.2 × 10^–4); Cluster 2: 2275 voxels (rho = − 0.51; p = 1.8 × 10^–4); Cluster 3: 2155 voxels (rho = − 0.52; p = 1.1 × 10^–4). These data are representative of voxel-level results.
^aAnalysis 1 included age, sex, gestational age at birth, birth weight, household income and second trimester maternal depression as covariates.
^bAnalysis 2 included age, sex, gestational age at birth, birth weight, household income, second trimester maternal depression as well as postnatal maternal depression and anxiety symptoms as covariates.
^cCluster peak.

Quick links

Search