Table 2 Associations of free form indoxyl sulfate and selected cardiovascular protein biomarkers in the multivariate linear regression model.

From: The relationship of indoxyl sulfate and p-cresyl sulfate with target cardiovascular proteins in hemodialysis patients

 

β coefficient (95% CI)

p value

C–C motif chemokine 15

− 0.53 (− 0.71 to − 0.35)

< 0.001

Complement component C1q receptor

− 0.14 (− 0.20 to − 0.09)

< 0.001

Perlecan

− 0.05 (− 0.07 to − 0.03)

< 0.001

Bleomycin hydrolase

− 0.22 (− 0.34 to − 0.11)

< 0.001

CD166 antigen

− 0.15 (− 0.23 to − 0.07)

< 0.001

SLAM family member 5

− 0.13 (− 0.22 to − 0.05)

0.002

Fibroblast growth factor 23

0.63 (0.23–1.04)

0.002

  1. Associations of baseline free form indoxyl sulfate with selected protein biomarker NPX value using multivariate linear regression model adjusting for age, sex, hemodialysis duration, cause of end-stage renal disease, arteriovenous shunt type, comorbidities (diabetes mellitus, hypertension, and dyslipidemia), medications (antiplatelet/warfarin, anti-hypertensive drugs, diabetic treatment drugs), and laboratory data (calcium, phosphate, high sensitivity C-reactive protein, and Kt/V).
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