Figure 7
Growth inhibition and defective progression of P. falciparum due to TMX treatment. (A) Graph showing growth inhibition of Pf3D7 and (B) PfRKL9 in presence of TMX with IC50 8.3 µM, (C) Graph showing percent inhibition in presence of TMX and chloroquine as positive control (D) Giemsa images showing hindered progression (44 hpi) and invasion (2nd cycle) of Pf3D7 with the relative percentages of ring formed and uninvaded merozoites in 2nd cycle of infection in control and TMX treated culture, scale bar represents distance of 5 µm (analysis of images by ImageJ; imagej.nih.gov) (E) Graph showing percent ratio of ring, trophozoite and schizonts at different time points post invasion for control and TMX treated culture. Data are represented as mean ± SD of at least three independent experiments.
