Table 4 Evaluation of acute eye irritation about the 10% EW of BE.
No | Areas | Eyes without washing | Eyes were washed at 4 s | Eyes were washed at 30 s | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Irritation response scores | |||||||||||||||||||||||||||||
1 h | 24 h | 48 h | 72 h | 4 d | 7 d | 1 h | 24 h | 48 h | 72 h | 1 h | 24 h | 48 h | 72 h | ||||||||||||||||
T | CK | T | CK | T | CK | T | CK | T | CK | T | CK | T | CK | T | CK | T | CK | T | CK | T | CK | T | CK | T | CK | T | CK | ||
1 | Conjunctiva | 8 | 0 | 10 | 0 | 10 | 0 | 8 | 0 | 6 | 0 | 0 | 0 | 6 | 0 | 4 | 0 | 2 | 0 | 0 | 0 | 8 | 0 | 6 | 0 | 4 | 0 | 0 | 0 |
Iris | 0 | 0 | 0 | 0 | 5 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Cornea | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Score | 8 | 0 | 10 | 0 | 15 | 0 | 13 | 0 | 6 | 0 | 0 | 0 | 6 | 0 | 4 | 0 | 2 | 0 | 0 | 0 | 8 | 0 | 6 | 0 | 4 | 0 | 0 | 0 | |
2 | Conjunctiva | 6 | 0 | 10 | 0 | 8 | 0 | 6 | 0 | 4 | 0 | 0 | 0 | 8 | 0 | 4 | 0 | 2 | 0 | 0 | 0 | 8 | 0 | 6 | 0 | 2 | 0 | 0 | 0 |
Iris | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Cornea | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Score | 6 | 0 | 10 | 0 | 8 | 0 | 6 | 0 | 4 | 0 | 0 | 0 | 8 | 0 | 4 | 0 | 2 | 0 | 0 | 0 | 8 | 0 | 6 | 0 | 2 | 0 | 0 | 0 | |
3 | Conjunctiva | 6 | 0 | 10 | 0 | 10 | 0 | 6 | 0 | 6 | 0 | 0 | 0 | 6 | 0 | 4 | 0 | 2 | 0 | 0 | 0 | 6 | 0 | 6 | 0 | 2 | 0 | 0 | 0 |
Iris | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Cornea | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Score | 6 | 0 | 10 | 0 | 15 | 0 | 6 | 0 | 6 | 0 | 0 | 0 | 6 | 0 | 4 | 0 | 2 | 0 | 0 | 0 | 6 | 0 | 6 | 0 | 2 | 0 | 0 | 0 | |
4 | Conjunctiva | 6 | 0 | 6 | 0 | 6 | 0 | 6 | 0 | 2 | 0 | 0 | 0 | 6 | 0 | 4 | 0 | 2 | 0 | 0 | 0 | 8 | 0 | 6 | 0 | 4 | 0 | 0 | 0 |
Iris | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Cornea | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Score | 6 | 0 | 6 | 0 | 6 | 0 | 6 | 0 | 2 | 0 | 0 | 0 | 6 | 0 | 4 | 0 | 2 | 0 | 0 | 0 | 8 | 0 | 6 | 0 | 4 | 0 | 0 | 0 | |
Total scores | 26 | 0 | 36 | 0 | 44 | 0 | 31 | 0 | 18 | 0 | 0 | 0 | 26 | 0 | 16 | 0 | 6 | 0 | 0 | 0 | 30 | 0 | 24 | 0 | 12 | 0 | 0 | 0 | |
Average irritation index | 6.5 | 9.0 | 11.0 | 7.75 | 4.5 | 0.0 | 6.5 | 4.0 | 1.5 | 0.0 | 7.5 | 6.0 | 3.0 | 0.0 | |||||||||||||||
Results | I.A.O.I. = 11.0; M.I.O.I. = 4.5; Mild and moderate irritation | I.A.O.I. = 6.5; M.I.O.I. = 1.5; Mild irritation | I.A.O.I. = 7.5; M.I.O.I. = 3.0; Mild irritation | ||||||||||||||||||||||||||
