Figure 1

Lexis diagram of populations of women with measured degree of skewed X-inactivation. Blue: 1895 birth cohort with repeated measures at the latest follow-up participation. Green: 1905 birth cohort (cross-sectional). Note There are no repeated measures, thus the 1905 cohort is not included in longitudinal studies. Purple: 1915 birth cohort (cross-sectional). Red: LSADT with repeated measures at follow-up. Gray: MADT (cross-sectional).