Figure 3

Cross-sectionally and longitudinally estimated changes in degree of skewed X-chromosome inactivation (DS) with age. Ten-year longitudinal changes of DS at baseline (1997) and follow-up (2007) in LSADT. Cross-sectional age changes were estimated using the LSADT (1997) and the 1905 birth cohort at 93 years of age and the 1895 centenarians.