Figure 2
From: Quantifying cell death induced by doxorubicin, hyperthermia or HIFU ablation with flow cytometry
Experimental images of ablated ex-vivo bovine liver. LEFT: N = 3 HIFU lesions for each of H = High = 8.2 MPa (peak-to-peak), M = Medium = 7.3 MPa and L = Low = 6.3 MPa acoustic pressures obtained in freshly harvested degassed ex vivo bovine liver. Liver tissue remains in watertight tissue holder with the acoustic window removed and has been sliced transversely at the axial focus (2 cm depth). Lesions for each pressure regime are staggered across rows to help locate the (more subtle) low power lesions relative to the other lesions. RIGHT: A biopsy sample of 6.2 mg liver mass exposed to low HIFU pressures obtained from the L1 lesion before (TOP) and after (BOTTOM) physical disaggregation using crossed scalpels in petri dish, prior to enzymatic digestion.
