Figure 3 | Scientific Reports

Figure 3

From: rs1944919 on chromosome 11q23.1 and its effector genes COLCA1/COLCA2 confer susceptibility to primary biliary cholangitis

Figure 3

Effects of rs1944919 on gene expression in knock-in clones generated using the CRISPR/Cas9 system. Expression levels of COLCA1 (A), COLCA2 (B), and POU2AF1 (C) in rs1944919-G/G and rs1944919-T/T knock-in clones of the Raji cell line. Expression levels of COLCA1 (D), COLCA2 (E), and POU2AF1 (F) in rs1944919-G/G and rs1944919-T/T knock-in clones of the Jurkat cell line. *P < 0.01 (Mann–Whitney U test).

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