Figure 2

3D structure and trajectory from MD simulation of Spike protein of SARS-CoV-2 and variants. (A) 3D Structural conformation of D614G (pink) next, the zoom of the amino acid G614 is shown in pink while the WT residue is indicated in blue. (B) 3D structure of H49Y (purple), the zoom of the amino acid variant Y49 is shown in purple, the WT residue is shown in the sticks in blue. (C) 3D structure of T573I (cyan) the zoom of the residue variant I573 is shown cyan while the WT residue T573 is indicated in blue sticks. (D) 3D structure of wild type S protein is shown in blue. Axes: X, red; Y, green; Z, blue. The structural analysis was carried out by RMSD (E), Radius of gyration (F) and the RMSF (G). The trajectories of the WT are shown in navy blue, D614G are shown in purple, H49Y are shown in blue and T573I are shown in yellow.