Figure 6
Molecular docking of most populated cluster conformation of spike proteins and mutants with experimentally proven compounds. General view of the binding pose obtained by docking of (A) cepharanthine, (B) hydroxychloroquine, (C) nelfinavir with wild type spike protein (green ribbon), D614G (cyan ribbon), H49Y (magenta ribbon) and T573I (yellow ribbon). Also, the interactions are between cepharanthine (wheat sticks) with (D) wild type spike protein, (E) D614G, (F) H49Y and (G) T573I; and hydroxychloroquine (orange sticks) with (H) wild type spike protein, (I) D614G, (J) H49Y and (K) T573I; and nelfinavir (raspberry sticks) with (L) wild type spike protein, (M) D614G, (N) H49Y and (O) T573I.
