Table 1 Nanoparticle tracking assessment of BSA-DF and freeze dried/reconstituted BSA-DF nanoparticles from multiple fabrication lots (3).

From: Influence of bound dodecanoic acid on the reconstitution of albumin nanoparticles from a lyophilized state

 

Mean diameter (nm)

D10 (nm)

D50 (nm)

D90 (nm)

Span

Pre-lyophilized BSA-DF nanoparticles

Mean ± SD

93 ± 1

71 ± 1

84 ± 2

108 ± 1

0.44 ± 0.03

COV (%)

1.1

1.4

2.4

1.0

6.8

Reconstituted BSA-DF nanoparticles

Mean ± SD

109 ± 1

81 ± 4

94 ± 2

143 ± 5

0.66 ± 0.03

COV (%)

1.0

4.8

2.1

3.5

4.5

  1. SD standard deviation of the mean.
Back to article page